2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. DNA Alkylator/Crosslinker
  5. DNA Alkylator/Crosslinker Activator

DNA Alkylator/Crosslinker Activator

DNA Alkylator/Crosslinker Activator (1):

Cat. No. Product Name Effect Purity
  • HY-W848341
    Clomesone
    		Activator
    Clomesone (NSC 338947) is a compound with antitumor activity. Clomesone induces the formation of cross-links between DNA strands in cell lines. Clomesone is inactive against most human colorectal cancer solid tumor cell lines in vitro, has no significant activity against mouse tumors in vivo, and is accompanied by bone marrow suppression. Its pharmacokinetic behavior indicates that it cannot reach effective concentrations at the tumor site.